Hughes Consulting is now Salas O’Brien
Same team. Same service. Expanded resources.
Hughes Consulting merged with Salas O’Brien in 2024 to expand capabilities and coverage throughout the pharmaceutical and biotechnology sectors. Our established leadership and talented team will continue delivering innovative service, consulting, and project execution from our Raleigh, North Carolina office.
Leadership focus. Solutions by design.
We focus on leadership-driven culture: accountability, integrity, and a service mindset. We care about earning trust and instilling confidence that we will get the job done right, ultimately keeping the patient’s well-being top of mind. Our team enthusiastically embraces cutting-edge solutions for unique challenges every day.
Case studies
Masterful process design advances gene therapy manufacturing
Salas O’Brien provided comprehensive engineering and design services for Pfizer’s new gene therapy manufacturing facility. Our team served as subject matter experts in drug product manufacturing, supporting the commissioning and validation of aseptic filling equipment.
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Optimizing clean-in-place systems for enhanced production efficiency
Salas O’Brien provided comprehensive process engineering and design services for a new clean-n-place (CIP) system. We designed and distributed CIP systems across two drug substance manufacturing buildings, with our team as the lead consultant. Our services included specifying, purchasing, and conducting factory acceptance tests (FAT) for four CIP superskids.
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Expanding production capabilities with strategic facility upgrades
Salas O’Brien supplied engineering support to a leading pharmaceutical manufacturer to expand their site compounding suite for new drug product operations. The expansion included strategically allocating space and routing utilities for a new fill line installation. Our team of provided a review of all design packages and feasibility studies.
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Highlighted services include
We are engineered for impact® with optimized solutions for complex challenges:
Facility engineering services
Salas O’Brien provides full-service mechanical, electrical, plumbing, and fire protection design (MEP) services to deliver complete facilities design. Whether our clients require modifications to existing buildings, or the design of entire greenfield facilities, we can accommodate needs in a timely and efficient manner. Learn more.
Process engineering & design
Our process engineering is a specialized field of engineering that focuses on the design, development, optimization, and management of industrial processes. It involves applying scientific and engineering principles to design, improve, and troubleshoot processes in a wide range of industries, including chemical, pharmaceutical, food and beverage, and oil and gas. Learn more.
Digital & automation
Salas O’Brien combines deep engineering expertise with cutting-edge technology to help clients operate smarter, faster, and more sustainably. From simulation-led design and digital twin technology to process modernization and smart manufacturing, we understand the intricacies of digitizing your facility. Learn more.
